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Aurora magazine

Paracetamol use in pregnancy may harm foetus

Paracetamol in pregnancy interferes with the development of the fetus. In particular, the drug would have negative consequences on male sexual behavior. It is the discovery of the team of David Møbjerg Kristensen of the University of Copenhagen. For the time being, the studies have been limited to the observation of animal models, but they still raise an important problem.

Paracetamol is one of the most used painkillers and doctors consider it safe for pregnant women as well. The study in question and the previous ones, always conducted on animal models, raise a question about it. Other studies have shown that fetal exposure to the drug may alter testosterone production. This study analyzes possible changes in sexual behavior.

The researchers administered paracetamol to pregnant guinea pigs. The dosages used were equivalent to those recommended for human puerperers. They then followed the male males from birth to adulthood. Cavities exposed to paracetamol in the fetal phase were found to be incapable of clumping like the other. According to the study, the drug has interfered with the development of male characteristics, with adulthood in adulthood.

he reasons for abnormal sexual behavior may be low in testosterone levels. Testosterone plays a key role in male sexual development. Mice exposed to paracetamol had less testosterone, were less aggressive and less active on the sexual level. In addition, the cerebral area that controls the sex drive was smaller.

Discovery could change the guidelines for taking the drug in pregnancy. According to the authors, paracetamol should be taken only in extreme cases.